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- Title
A phase 2 study of (99m)Tc-tilmanocept in the detection of sentinel lymph nodes in melanoma and breast cancer.
- Authors
Leong, Stanley P L; Kim, Julian; Ross, Merrick; Faries, Mark; Scoggins, Charles R; Metz, Wendy L Rich; Cope, Frederick O; Orahood, Richard C
- Abstract
Several (99m)Tc-labeled agents that are not approved by the U.S. Food and Drug Administration are used for lymphatic mapping. A new low-molecular-weight mannose receptor-based, reticuloendothelial cell-directed, (99m)Tc-labeled lymphatic imaging agent, (99m)Tc-tilmanocept, was used for lymphatic mapping of sentinel lymph nodes (SLNs) from patients with primary breast cancer or melanoma malignancies. This novel molecular species provides the basis for potentially enhanced SLN mapping reliability.
- Publication
Annals of surgical oncology, 2011, Vol 18, Issue 4, p961
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-010-1524-z