We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Jun activation domain binding protein 1 is overexpressed from the very early stages of hepatocarcinogenesis.
- Authors
Yachida, Shinichi; Imaida, Katsumi; Yokohira, Masanao; Hashimoto, Nozomi; Suzuki, Shugo; Okano, Keiichi; Wakabayashi, Hisao; Maeta, Hajime; Suzuki, Yasuyuki
- Abstract
As is known for many types of human cancers, the hepatocellular carcinoma (HCC) associated with chronic liver disease shows an obvious multistage process of tumor progression. Despite the demonstrated importance of cell-cycle regulators in tumor biology, there have only been a few studies of their role in multistep hepatocarcinogenesis. Recently, we reported that a high level of p27(Kip1) expression is evident from the very early stages of hepatocarcinogenesis.
- Publication
Annals of surgical oncology, 2010, Vol 17, Issue 12, p3386
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-010-1197-7