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- Title
Chromogranin A--biological function and clinical utility in neuro endocrine tumor disease.
- Authors
Modlin, Irvin M; Gustafsson, Bjorn I; Moss, Steven F; Pavel, Marianne; Tsolakis, Apostolos V; Kidd, Mark
- Abstract
Neuroendocrine tumors (NETs) are a form of cancer that differ from other neoplasia in that they synthesize, store, and secrete peptides, e.g., chromogranin A (CgA) and amines. A critical issue is late diagnosis due to failure to identify symptoms or to establish the biochemical diagnosis. We review here the utility of CgA measurement in NETs and describe its biological role and the clinical value of its measurement.
- Publication
Annals of surgical oncology, 2010, Vol 17, Issue 9, p2427
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-010-1006-3