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- Title
Relationship of insulin-like growth factors system gene polymorphisms with the susceptibility and pathological development of hepatocellular carcinoma.
- Authors
Weng, Chia-Jui; Hsieh, Yi-Hsien; Tsai, Chiung-Man; Chu, Yin-Hung; Ueng, Kwo-Chang; Liu, Yu-Fan; Yeh, Yuan-Hung; Su, Shih-Chi; Chen, Yi-Chen; Chen, Mu-Kuan; Yang, Shun-Fa
- Abstract
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death worldwide. The insulin-like growth factors (IGFs) system consists of a group of proteins which may induce cell proliferation and inhibit cell apoptosis through several signal pathways, leading to transformation of normal cells into cancer cells. However, the impact of genetic polymorphisms of the IGFs system on HCC has not been clarified.
- Publication
Annals of surgical oncology, 2010, Vol 17, Issue 7, p1808
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-009-0904-8