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- Title
Modified radical hysterectomy versus extrafascial hysterectomy in the treatment of stage I endometrial cancer: results from the ILIADE randomized study.
- Authors
Signorelli, Mauro; Lissoni, Andrea Alberto; Cormio, Gennaro; Katsaros, Dionyssios; Pellegrino, Antonio; Selvaggi, Luigi; Ghezzi, Fabio; Scambia, Giovanni; Zola, Paolo; Grassi, Roberto; Milani, Rodolfo; Giannice, Raffaella; Caspani, Giovanna; Mangioni, Costantino; Floriani, Irene; Rulli, Eliana; Fossati, Roldano
- Abstract
Five percent to 20% of stage I endometrial cancer patients undergoing total abdominal hysterectomy and bilateral salpingo-oophorectomy develop vaginal and pelvic recurrences. Adjuvant radiotherapy can improve locoregional control but not survival. This randomized trial aimed to determine whether a modified radical (Piver-Rutledge class II) hysterectomy can improve survival and locoregional control compared to the standard extrafascial (Piver-Rutledge class I) hysterectomy.
- Publication
Annals of surgical oncology, 2009, Vol 16, Issue 12, p3431
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-009-0736-6