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- Title
Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate.
- Authors
Reid, Alison H M; Attard, Gerhardt; Danila, Daniel C; Oommen, Nikhil Babu; Olmos, David; Fong, Peter C; Molife, L Rhoda; Hunt, Joanne; Messiou, Christina; Parker, Christopher; Dearnaley, David; Swennenhuis, Joost F; Terstappen, Leon W M M; Lee, Gloria; Kheoh, Thian; Molina, Arturo; Ryan, Charles J; Small, Eric; Scher, Howard I; de Bono, Johann S
- Abstract
The principal objective of this trial was to evaluate the antitumor activity of abiraterone acetate, an oral, specific, irreversible inhibitor of CYP17 in docetaxel-treated patients with castration-resistant prostate cancer (CRPC).
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Vol 28, Issue 9, p1489
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2009.24.6819