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- Title
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
- Authors
Wick, Wolfgang; Hartmann, Christian; Engel, Corinna; Stoffels, Mandy; Felsberg, Jörg; Stockhammer, Florian; Sabel, Michael C; Koeppen, Susanne; Ketter, Ralf; Meyermann, Richard; Rapp, Marion; Meisner, Christof; Kortmann, Rolf D; Pietsch, Torsten; Wiestler, Otmar D; Ernemann, Ulrike; Bamberg, Michael; Reifenberger, Guido; von Deimling, Andreas; Weller, Michael
- Abstract
The standard of care for anaplastic gliomas is surgery followed by radiotherapy. The NOA-04 phase III trial compared efficacy and safety of radiotherapy followed by chemotherapy at progression with the reverse sequence in patients with newly diagnosed anaplastic gliomas.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 35, p5874
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2009.23.6497