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- Title
Conditional survival and the choice of conditioning set for patients with colon cancer: an analysis of NSABP trials C-03 through C-07.
- Authors
Zamboni, Beth A; Yothers, Greg; Choi, Mehee; Fuller, Clifton D; Dignam, James J; Raich, Peter C; Thomas, Charles R, Jr; O'Connell, Michael J; Wolmark, Norman; Wang, Samuel J
- Abstract
Colon cancer overall survival (OS) is usually computed from the time of diagnosis. Survival gives the initial prognosis but does not reflect how prognosis changes with changing hazard rates over time. Conditional survival (probability of surviving y additional years given they have survived x years [CS or OS|OS]) is an alternative measure that accounts for elapsed time since diagnosis, providing more relevant prognostic information. We extend the concept of CS to condition on the set of patients alive, recurrence-free, and second primary cancer-free (disease-free survival [OS|DFS]).
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Vol 28, Issue 15, p2544
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2009.23.0573