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- Title
Melanoma prognostic model using tissue microarrays and genetic algorithms.
- Authors
Gould Rothberg, Bonnie E; Berger, Aaron J; Molinaro, Annette M; Subtil, Antonio; Krauthammer, Michael O; Camp, Robert L; Bradley, William R; Ariyan, Stephan; Kluger, Harriet M; Rimm, David L
- Abstract
As a result of the questionable risk-to-benefit ratio of adjuvant therapies, stage II melanoma is currently managed by observation because available clinicopathologic parameters cannot identify the 20% to 60% of such patients likely to develop metastatic disease. Here, we propose a multimarker molecular prognostic assay that can help triage patients at increased risk of recurrence.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 34, p5772
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2009.22.8239