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- Title
Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers.
- Authors
Kurian, Allison W; Sigal, Bronislava M; Plevritis, Sylvia K
- Abstract
Women with BRCA1/2 mutations inherit high risks of breast and ovarian cancer; options to reduce cancer mortality include prophylactic surgery or breast screening, but their efficacy has never been empirically compared. We used decision analysis to simulate risk-reducing strategies in BRCA1/2 mutation carriers and to compare resulting survival probability and causes of death.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Vol 28, Issue 2, p222
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2009.22.7991