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- Title
Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck.
- Authors
Lassen, Pernille; Eriksen, Jesper G; Hamilton-Dutoit, Stephen; Tramm, Trine; Alsner, Jan; Overgaard, Jens
- Abstract
A subset of head and neck cancers is associated with the human papillomavirus (HPV). Viral infection is closely correlated with expression of p16(INK4A) in these tumors. We evaluated p16(INK4A) as a prognostic marker of treatment response and survival in a well-defined and prospectively collected cohort of patients treated solely with conventional radiotherapy in the Danish Head and Neck Cancer Group (DAHANCA) 5 trial.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 12, p1992
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.20.2853