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- Title
Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study.
- Authors
Dai, Qi; Gao, Yu-Tang; Shu, Xiao-Ou; Yang, Gong; Milne, Ginger; Cai, Qiuyin; Wen, Wanqing; Rothman, Nathaniel; Cai, Hui; Li, Honglan; Xiang, Yongbing; Chow, Wong-Ho; Zheng, Wei
- Abstract
Increased reactive oxygen species may exhaust the antioxidant capability of human defense systems, leading to oxidative stress and cancer development. Urinary F2-isoprostanes, secondary end products of lipid peroxidation, are more accurate markers of oxidative stress than other available biomarkers. No prospective study has investigated whether levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP) and its metabolite 2,3-dinor-5,6-dihydro-15-F(2t)-IsoP (15-F(2t)-IsoPM) are related to breast cancer risk.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 15, p2482
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.19.7970