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- Title
PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer.
- Authors
Ogino, Shuji; Nosho, Katsuhiko; Kirkner, Gregory J; Shima, Kaori; Irahara, Natsumi; Kure, Shoko; Chan, Andrew T; Engelman, Jeffrey A; Kraft, Peter; Cantley, Lewis C; Giovannucci, Edward L; Fuchs, Charles S
- Abstract
PIK3CA mutation and subsequent activation of the AKT pathway play an important role in colorectal carcinogenesis. However, little is known about the prognostic role of PIK3CA mutation in colon cancer.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 9, p1477
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.18.6544