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- Title
Phase II trial of sorafenib in metastatic thyroid cancer.
- Authors
Kloos, Richard T; Ringel, Matthew D; Knopp, Michael V; Hall, Nathan C; King, Mark; Stevens, Robert; Liang, Jiachao; Wakely, Paul E, Jr; Vasko, Vasyl V; Saji, Motoyasu; Rittenberry, Jennifer; Wei, Lai; Arbogast, Daria; Collamore, Minden; Wright, John J; Grever, Michael; Shah, Manisha H
- Abstract
Based on the pivotal role of Ras-Raf-MAP-ERK signaling and vascular endothelial growth factor (VEGF) in papillary thyroid cancer (PTC), we conducted a phase II clinical trial of sorafenib targeting RAF and VEGF receptor kinases in PTC.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 10, p1675
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.18.2717