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- Title
Meta-analysis of single-agent chemotherapy compared with combination chemotherapy as second-line treatment of advanced non-small-cell lung cancer.
- Authors
Di Maio, Massimo; Chiodini, Paolo; Georgoulias, Vassilis; Hatzidaki, Dora; Takeda, Koji; Wachters, Floris M; Gebbia, Vittorio; Smit, Egbert F; Morabito, Alessandro; Gallo, Ciro; Perrone, Francesco; Gridelli, Cesare
- Abstract
Doublet chemotherapy is more effective than single-agent as first-line treatment of advanced non-small-cell lung cancer (NSCLC). As second-line treatment, several randomized trials have been performed comparing single-agent with doublet chemotherapy, but each trial had an insufficient power to detect potentially relevant differences in survival.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 11, p1836
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.17.5844