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- Title
Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with Carboplatin and Paclitaxel plus bevacizumab.
- Authors
Sandler, Alan B; Schiller, Joan H; Gray, Robert; Dimery, Isaiah; Brahmer, Julie; Samant, Meghna; Wang, Lisa I; Johnson, David H
- Abstract
Severe (grade >or= 3) pulmonary hemorrhage (PH) in advanced non-small-cell lung cancer was observed in two prospective, randomized, phase II (N = 99) and phase III (N = 878) trials of bevacizumab plus carboplatin and paclitaxel. Retrospective case-control and cohort analyses were conducted to identify associated radiographic and clinical risk factors for PH.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Vol 27, Issue 9, p1405
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.16.2412