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- Title
Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group.
- Authors
Meyers, Paul A; Schwartz, Cindy L; Krailo, Mark D; Healey, John H; Bernstein, Mark L; Betcher, Donna; Ferguson, William S; Gebhardt, Mark C; Goorin, Allen M; Harris, Michael; Kleinerman, Eugenie; Link, Michael P; Nadel, Helen; Nieder, Michael; Siegal, Gene P; Weiner, Michael A; Wells, Robert J; Womer, Richard B; Grier, Holcombe E; Children's Oncology Group
- Abstract
To compare three-drug chemotherapy with cisplatin, doxorubicin, and methotrexate with four-drug chemotherapy with cisplatin, doxorubicin, methotrexate, and ifosfamide for the treatment of osteosarcoma. To determine whether the addition of muramyl tripeptide (MTP) to chemotherapy enhances event-free survival (EFS) and overall survival in newly diagnosed patients with osteosarcoma.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Vol 26, Issue 4, p633
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2008.14.0095