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- Title
Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab.
- Authors
Khambata-Ford, Shirin; Garrett, Christopher R; Meropol, Neal J; Basik, Mark; Harbison, Christopher T; Wu, Shujian; Wong, Tai W; Huang, Xin; Takimoto, Chris H; Godwin, Andrew K; Tan, Benjamin R; Krishnamurthi, Smitha S; Burris, Howard A, 3rd; Poplin, Elizabeth A; Hidalgo, Manuel; Baselga, Jose; Clark, Edwin A; Mauro, David J
- Abstract
The antiepidermal growth factor receptor (EGFR) antibody cetuximab shows activity in multiple epithelial tumor types; however, responses are seen in only a subset of patients. This study was conducted to identify markers that are associated with disease control in patients treated with cetuximab.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Vol 25, Issue 22, p3230
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2006.10.5437