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- Title
Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.
- Authors
Ruzzo, Annamaria; Graziano, Francesco; Loupakis, Fotios; Rulli, Eliana; Canestrari, Emanuele; Santini, Daniele; Catalano, Vincenzo; Ficarelli, Rita; Maltese, Paolo; Bisonni, Renato; Masi, Gianluca; Schiavon, Gaia; Giordani, Paolo; Giustini, Lucio; Falcone, Alfredo; Tonini, Giuseppe; Silva, Rosarita; Mattioli, Rodolfo; Floriani, Irene; Magnani, Mauro
- Abstract
The objective is to investigate whether polymorphisms with putative influence on fluorouracil/oxaliplatin activity are associated with clinical outcomes of patients with advanced colorectal cancer treated with first-line oxaliplatin, folinic acid, and fluorouracil palliative chemotherapy.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Vol 25, Issue 10, p1247
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2006.08.1844