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- Title
Paclitaxel plus Ifosfamide followed by high-dose carboplatin plus etoposide in previously treated germ cell tumors.
- Authors
Kondagunta, G Varuni; Bacik, Jennifer; Sheinfeld, Joel; Bajorin, Dean; Bains, Manjit; Reich, Lillian; Deluca, John; Budnick, Amy; Ishill, Nicole; Mazumdar, Madhu; Bosl, George J; Motzer, Robert J
- Abstract
To evaluate the optimal dose of carboplatin as well as the efficacy and tolerability of sequential, dose-intense chemotherapy with paclitaxel and ifosfamide followed by carboplatin and etoposide (TICE) plus peripheral-blood stem-cell (PBSC) support in patients with germ cell tumors (GCT) who are likely to experience treatment failure with conventional-dose salvage treatment. This prospective trial followed a similarly designed report of TICE, which used a different means of carboplatin dosing.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Vol 25, Issue 1, p85
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2006.06.9401