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- Title
Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphoma.
- Authors
Sagaert, Xavier; de Paepe, Pascale; Libbrecht, Louis; Vanhentenrijk, Vera; Verhoef, Gregor; Thomas, Jose; Wlodarska, Iwona; De Wolf-Peeters, Christiane
- Abstract
Gene expression profiling studies have reported upregulated mRNA expression of forkhead box protein P1 (FOXP1) in response to normal B-cell activation and high expression in a poor prognosis subtype of diffuse large B-cell lymphoma (DLBCL). Recently, it was also found that FOXP1 rearrangements and expression of its protein occur in mucosa-associated lymphoid tissue (MALT) lymphomas. In this study, we investigated FOXP1 expression in its relationship to morphology, genetic features, and prognosis in a series of 70 MALT lymphomas.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Vol 24, Issue 16, p2490
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2006.05.6150