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- Title
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer.
- Authors
Low, Jennifer A; Wedam, Suparna B; Lee, James J; Berman, Arlene W; Brufsky, Adam; Yang, Sherry X; Poruchynsky, Marianne S; Steinberg, Seth M; Mannan, Nitin; Fojo, Tito; Swain, Sandra M
- Abstract
Ixabepilone (BMS-247550) is an epothilone B analog that stabilizes microtubules and has antitumor activity in taxane-refractory patients in phase I studies. In a phase II trial, we evaluated the efficacy and safety of ixabepilone in women with metastatic and locally advanced breast cancer.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 12, p2726
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.10.024