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- Title
Graft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning.
- Authors
Baron, Frédéric; Maris, Michael B; Sandmaier, Brenda M; Storer, Barry E; Sorror, Mohamed; Diaconescu, Razvan; Woolfrey, Ann E; Chauncey, Thomas R; Flowers, Mary E D; Mielcarek, Marco; Maloney, David G; Storb, Rainer
- Abstract
We have used a nonmyeloablative conditioning regimen consisting of total-body irradiation (2 Gy) with or without fludarabine (30 mg/m(2)/d for 3 days) for related and unrelated hematopoietic cell transplantation (HCT) in patients with hematologic malignancies who were not candidates for conventional HCT because of age, medical comorbidities, or preceding high-dose HCT. This approach relied on graft-versus-tumor (GVT) effects for control of malignancy.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 9, p1993
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.08.136