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Title
Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.
Authors
Rudek, Michelle A; Zhao, Ming; He, Ping; Hartke, Carol; Gilbert, Jill; Gore, Steven D; Carducci, Michael A; Baker, Sharyn D
Abstract
To characterize the pharmacokinetic behavior of 5-azacitidine (5-AC), a cytidine nucleoside analog, when given with phenylbutyrate, a histone deaceytlase inhibitor.
Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 17, p3906