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- Title
Phase III randomized trial of conventional-dose chemotherapy with or without high-dose chemotherapy and autologous hematopoietic stem-cell rescue as first-line treatment for patients with poor-prognosis metastatic germ cell tumors.
- Authors
Motzer, Robert J; Nichols, Craig J; Margolin, Kim A; Bacik, Jennifer; Richardson, Paul G; Vogelzang, Nicholas J; Bajorin, Dean F; Lara, Primo N, Jr; Einhorn, Lawrence; Mazumdar, Madhu; Bosl, George J
- Abstract
To investigate the role of high-dose chemotherapy (HDCT) as first-line treatment in patients with metastatic germ cell tumor (GCT) and poor-prognostic clinical features. Serum tumor marker decline during chemotherapy was assessed prospectively as a predictor of treatment outcome.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Vol 25, Issue 3, p247
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.05.4528