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- Title
Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis.
- Authors
Lin, Daniel W; Coleman, Ilsa M; Hawley, Sarah; Huang, Chung Y; Dumpit, Ruth; Gifford, David; Kezele, Philip; Hung, Hau; Knudsen, Beatrice S; Kristal, Alan R; Nelson, Peter S
- Abstract
Measurements of tissue gene expression are increasingly used for disease stratification, clinical trial eligibility, and assessment of neoadjuvant therapy response. However, the method of tissue acquisition alone could significantly influence the expression of specific transcripts or proteins. This study examines whether there are transcript alterations associated with surgical resection of the prostate gland by radical retropubic prostatectomy.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Vol 24, Issue 23, p3763
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.05.1458