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- Title
Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: expression of angiopoietin-2 represents an independent prognostic factor for overall survival.
- Authors
Loges, Sonja; Heil, Gerhard; Bruweleit, Melanie; Schoder, Volker; Butzal, Martin; Fischer, Uta; Gehling, Ursula M; Schuch, Gunter; Hossfeld, Dieter K; Fiedler, Walter
- Abstract
Bone marrow neoangiogenesis plays an important pathogenetic and possible prognostic role in acute myeloid leukemia (AML). Members of the vascular endothelial growth factor (VEGF) and angiopoietin family represent the most specific inducers of angiogenesis secreted by AML blasts. We therefore correlated expression of angiogenic factors with clinical variables.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 6, p1109
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.05.058