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- Title
Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results.
- Authors
Rugo, Hope S; Herbst, Roy S; Liu, Glenn; Park, John W; Kies, Merrill S; Steinfeldt, Heidi M; Pithavala, Yazdi K; Reich, Steven D; Freddo, James L; Wilding, George
- Abstract
We studied the safety, clinical activity, and pharmacokinetics (PK) of AG-013736, an oral receptor tyrosine kinase inhibitor of vascular endothelial cell growth factor, platelet-derived growth factor, and c-Kit, in patients with advanced cancer.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 24, p5474
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.04.192