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- Title
Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.
- Authors
Goetz, Matthew P; Rae, James M; Suman, Vera J; Safgren, Stephanie L; Ames, Matthew M; Visscher, Daniel W; Reynolds, Carol; Couch, Fergus J; Lingle, Wilma L; Flockhart, David A; Desta, Zeruesenay; Perez, Edith A; Ingle, James N
- Abstract
Polymorphisms in tamoxifen metabolizing genes affect the plasma concentration of tamoxifen metabolites, but their effect on clinical outcome is unknown.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 36, p9312
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.03.3266