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- Title
Phase I/II trial assessing bortezomib and melphalan combination therapy for the treatment of patients with relapsed or refractory multiple myeloma.
- Authors
Berenson, James R; Yang, Hank H; Sadler, Karen; Jarutirasarn, Supol G; Vescio, Robert A; Mapes, Russell; Purner, Matthew; Lee, Shi-pyng; Wilson, Joanna; Morrison, Blake; Adams, Julian; Schenkein, David; Swift, Regina
- Abstract
Bortezomib has shown synergy with melphalan in preclinical models. We assessed the safety, tolerability, and response rate in a dose-escalation study of this combination for relapsed or refractory multiple myeloma patients.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Vol 24, Issue 6, p937
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.03.2383