We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Topoisomerase IIalpha gene amplification predicts favorable treatment response to tailored and dose-escalated anthracycline-based adjuvant chemotherapy in HER-2/neu-amplified breast cancer: Scandinavian Breast Group Trial 9401.
- Authors
Tanner, Minna; Isola, Jorma; Wiklund, Tom; Erikstein, Björn; Kellokumpu-Lehtinen, Pirkko; Malmström, Per; Wilking, Nils; Nilsson, Jonas; Bergh, Jonas; Scandinavian Breast Group Trial 9401
- Abstract
Amplification of the HER-2/neu and topoisomerase IIalpha (TOP2A) genes has been linked to the effects of anthracyclines. Their role in predicting the outcome of anthracycline-based adjuvant chemotherapy for breast cancer patients has remained controversial.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Vol 24, Issue 16, p2428
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.02.9264