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- Title
Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study.
- Authors
Burtness, Barbara; Goldwasser, Meredith A; Flood, William; Mattar, Bassam; Forastiere, Arlene A; Eastern Cooperative Oncology Group
- Abstract
Therapy of recurrent/metastatic squamous cell carcinoma of the head and neck results in median progression-free survival (PFS) of 2 months. These cancers are rich in epidermal growth factor receptor (EGFR). We wished to determine whether the addition of cetuximab, which inhibits activation of EGFR, would improve PFS.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Vol 23, Issue 34, p8646
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2005.02.4646