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- Title
The addition of interleukin-6 soluble receptor and transforming growth factor beta1 improves a preoperative nomogram for predicting biochemical progression in patients with clinically localized prostate cancer.
- Authors
Kattan, Michael W; Shariat, Shahrokh F; Andrews, Ben; Zhu, Kuichun; Canto, Eduardo; Matsumoto, Kazumasa; Muramoto, Masatoshi; Scardino, Peter T; Ohori, Makoto; Wheeler, Thomas M; Slawin, Kevin M
- Abstract
Several preoperative prostate cancer nomograms have been developed that predict risk of progression using pretreatment prostate-specific antigen (PSA) level, clinical stage, and biopsy Gleason grade. We describe the development and performance of a new nomogram. The nomogram adds new markers to the standard clinical predictors that reflect the biologic behavior of prostate cancer: pretreatment plasma levels of interleukin-6 soluble receptor (IL6SR) and transforming growth factor beta1 (TGF-beta1).
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Vol 21, Issue 19, p3573
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2003.12.037