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- Title
Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study.
- Authors
Taylor, Roger E; Bailey, Clifford C; Robinson, Kath; Weston, Claire L; Ellison, David; Ironside, James; Lucraft, Helen; Gilbertson, Richard; Tait, Diana M; Walker, David A; Pizer, Barry L; Imeson, John; Lashford, Linda S; International Society of Paediatric Oncology; United Kingdom Children's Cancer Study Group
- Abstract
To determine whether preradiotherapy (RT) chemotherapy would improve outcome for Chang stage M0-1 medulloblastoma when compared with RT alone. Chemotherapy comprised vincristine 1.5 mg/m2 weekly for 10 weeks and four cycles of etoposide 100 mg/m2 daily for 3 days, and carboplatin 500 mg/m2 daily for 2 days alternating with cyclophosphamide 1.5 g/m2.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Vol 21, Issue 8, p1581
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2003.05.116