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- Title
Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis.
- Authors
Christiansen, D H; Andersen, M K; Pedersen-Bjergaard, J
- Abstract
To study mutations and loss of heterozygosity (LOH) of p53 in therapy-related myelodysplasia (t-MDS) and acute myeloid leukemia (t-AML).
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Vol 19, Issue 5, p1405
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2001.19.5.1405