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- Title
Single-arm, open-label phase II study of intravenously administered tirapazamine and radiation therapy for glioblastoma multiforme.
- Authors
Del Rowe, J; Scott, C; Werner-Wasik, M; Bahary, J P; Curran, W J; Urtasun, R C; Fisher, B
- Abstract
This phase II study tested the efficacy and safety of tirapazamine (Sanofi Synthelabo Research, Malvern, PA), a bioreductive agent, in glioblastoma multiforme (GBM) patients. The patients were staged according to a model constructed by a recursive partitioning analysis (RPA) of glioma patients in prior Radiation Therapy Oncology Group (RTOG) trials and compared with a matched standard population, as predicted by the model.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Vol 18, Issue 6, p1254
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.2000.18.6.1254