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- Title
Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04)
- Authors
Mamounas, E; Wieand, S; Wolmark, N; Bear, H D; Atkins, J N; Song, K; Jones, J; Rockette, H
- Abstract
Although the benefit from adjuvant chemotherapy has been clearly established in patients with Dukes' C colon cancer, such benefit has been questioned in patients with Dukes' B disease. To determine whether patients with Dukes' B disease benefit from adjuvant chemotherapy and to evaluate the magnitude of the benefit, compared with that observed in Dukes' C patients, we examined the relative efficacy of adjuvant chemotherapy according to Dukes' stage in four sequential National Surgical Adjuvant Breast and Bowel Project trials (C-01, C-02, C-03, and C-04) that compared different adjuvant chemotherapy regimens with each other or with no adjuvant treatment.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Vol 17, Issue 5, p1349
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1999.17.5.1349