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- Title
Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: initial results of intergroup 0114.
- Authors
Tepper, J E; O'Connell, M J; Petroni, G R; Hollis, D; Cooke, E; Benson, A B, 3rd; Cummings, B; Gunderson, L L; Macdonald, J S; Martenson, J A
- Abstract
The combination of radiation therapy with fluorouracil (5-FU)-based chemotherapy is generally accepted as appropriate postoperative therapy for patients with adenocarcinomas of the rectum that extend through the bowel wall or with lymph nodes positive for tumor. We attempted to determine whether the efficacy of this postoperative therapy could be improved by the addition of leucovorin and/or levamisole.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Vol 15, Issue 5, p2030
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1997.15.5.2030