We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Iodine-131-anti-B1 radioimmunotherapy for B-cell lymphoma.
- Authors
Kaminski, M S; Zasadny, K R; Francis, I R; Fenner, M C; Ross, C W; Milik, A W; Estes, J; Tuck, M; Regan, D; Fisher, S; Glenn, S D; Wahl, R L
- Abstract
The CD20 B-lymphocyte surface antigen expressed by B-cell lymphomas is an attractive target for radioimmunotherapy, treatment using radiolabeled antibodies. We conducted a phase I dose-escalation trial to assess the toxicity, tumor targeting, and efficacy of nonmyeloablative doses of an anti-CD20 monoclonal antibody (anti-B1) labeled with iodine-131 (131I) in 34 patients with B-cell lymphoma who had failed chemotherapy.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Vol 14, Issue 7, p1974
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1996.14.7.1974