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- Title
Pilot trial of infusional cyclophosphamide, doxorubicin, and etoposide plus didanosine and filgrastim in patients with human immunodeficiency virus-associated non-Hodgkin's lymphoma.
- Authors
Sparano, J A; Wiernik, P H; Hu, X; Sarta, C; Schwartz, E L; Soeiro, R; Henry, D H; Mason, B; Ratech, H; Dutcher, J P
- Abstract
To determine the following: (1) the feasibility of combining the antiretroviral didanosine (ddl) with a 96-hour continuous intravenous (IV) infusion of cyclophosphamide (800 mg/m2), doxorubicin (50 mg/m2), and etoposide (240 mg/m2) (CDE) plus filgrastim in patients with non-Hodgkin's lymphoma (NHL) associated with human immunodeficiency virus (HIV) infection; (2) the effect of ddl on CDE-induced myelosuppression and CD4 lymphopenia; and (3) the effect of CDE on serum p24 antigen and quantitative HIV blood cultures.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Vol 14, Issue 11, p3026
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1996.14.11.3026