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- Title
Dose-intensification of MVAC with recombinant granulocyte colony-stimulating factor as initial therapy in advanced urothelial cancer.
- Authors
Seidman, A D; Scher, H I; Gabrilove, J L; Bajorin, D F; Motzer, R J; O'Dell, M; Curley, T; Dershaw, D D; Quinlivan, S; Tao, Y
- Abstract
This study was undertaken to define an escalated dose schedule of methotrexate, vinblastine, doxorubicin, and cisplatin (E-MVAC) with hematopoietic growth-factor support, to define the ability to deliver E-MVAC with recombinant human granulocyte colony-stimulating factor (rhG-CSF) on 21- and 14-day schedules, and to assess the ability of rhG-CSF to maintain dose-intensity over four cycles of chemotherapy.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Vol 11, Issue 3, p408
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1993.11.3.408