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- Title
Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer.
- Authors
Paterson, A H; Powles, T J; Kanis, J A; McCloskey, E; Hanson, J; Ashley, S
- Abstract
Osteolytic metastases often give rise to hypercalcemia, fracture, and bone pain, and occur commonly in patients with recurrent breast cancer. We assessed the bisphosphonate, clodronate, which has proven to be a useful treatment for hypercalcemia and may be a potent inhibitor of tumor-induced osteolysis, for its effect on reducing the osseous complications of metastatic breast cancer.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Vol 11, Issue 1, p59
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1993.11.1.59