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- Title
Use of allogeneic hematopoietic stem-cell transplantation based on minimal residual disease response improves outcomes for children with relapsed acute lymphoblastic leukemia in the intermediate-risk group.
- Authors
Eckert, Cornelia; Henze, Günter; Seeger, Karlheinz; Hagedorn, Nikola; Mann, Georg; Panzer-Grümayer, Renate; Peters, Christina; Klingebiel, Thomas; Borkhardt, Arndt; Schrappe, Martin; Schrauder, André; Escherich, Gabriele; Sramkova, Lucie; Niggli, Felix; Hitzler, Johann; von Stackelberg, Arend
- Abstract
In children with intermediate risk of relapse of acute lymphoblastic leukemia (ALL), it is essential to identify patients in need of treatment intensification. We hypothesized that the prognosis of patients with unsatisfactory reduction of minimal residual disease (MRD) can be improved by allogeneic hematopoietic stem-cell transplantation (HSCT).
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Vol 31, Issue 21, p2736
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2012.48.5680