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- Title
Effect of donor KIR2DL1 allelic polymorphism on the outcome of pediatric allogeneic hematopoietic stem-cell transplantation.
- Authors
Bari, Rafijul; Rujkijyanont, Piya; Sullivan, Erin; Kang, Guolian; Turner, Victoria; Gan, Kwan; Leung, Wing
- Abstract
Killer-cell immunoglobulin-like receptors (KIRs) that regulate natural-killer cells are highly polymorphic. Some KIR2DL1 alleles encode receptors that have stronger signaling function than others. We tested the hypothesis that the clinical outcomes of allogeneic hematopoietic stem-cell transplantation (HSCT) could be affected by donor KIR2DL1 polymorphism.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Vol 31, Issue 30, p3782
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2012.47.4007