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- Title
MicroRNA signature obtained from the comparison of aggressive with indolent non-Hodgkin lymphomas: potential prognostic value in mantle-cell lymphoma.
- Authors
Goswami, Rashmi S; Atenafu, Eshetu G; Xuan, Yali; Waldron, Levi; Reis, Patricia P; Sun, Thomas; Datti, Alessandro; Xu, Wei; Kuruvilla, John; Good, David J; Lai, Raymond; Church, Alanna J; Lam, Wilson S; Baetz, Tara; Lebrun, David P; Sehn, Laurie H; Farinha, Pedro; Jurisica, Igor; Bailey, Denis J; Gascoyne, Randy D; Crump, Michael; Kamel-Reid, Suzanne
- Abstract
Mantle-cell lymphoma (MCL) has a variable natural history but is incurable with current therapies. MicroRNAs (miRs) are useful in prognostic assessment of cancer. We determined an miR signature defining aggressiveness in B-cell non-Hodgkin lymphomas (NHL) and assessed whether this signature aids in MCL prognosis.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Vol 31, Issue 23, p2903
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2012.45.3050