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- Title
Tissue platinum concentration and tumor response in non-small-cell lung cancer.
- Authors
Kim, Eric S; Lee, J Jack; He, Guangan; Chow, Chi-Wan; Fujimoto, Junya; Kalhor, Neda; Swisher, Stephen G; Wistuba, Ignacio I; Stewart, David J; Siddik, Zahid H
- Abstract
Platinum resistance is a major limitation in the treatment of advanced non-small-cell lung cancer (NSCLC). Reduced intracellular drug accumulation is one of the most consistently identified features of platinum-resistant cell lines, but clinical data are limited. We assessed the effects of tissue platinum concentrations on response and survival in NSCLC.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Vol 30, Issue 27, p3345
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2011.40.8120