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- Title
Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: a comprehensive cytokine profiling study.
- Authors
Tefferi, Ayalew; Vaidya, Rakhee; Caramazza, Domenica; Finke, Christy; Lasho, Terra; Pardanani, Animesh
- Abstract
Abnormal cytokine expression accompanies myelofibrosis and might be a therapeutic target for Janus-associated kinase (JAK) inhibitor drugs. This study describes the spectrum of plasma cytokine abnormalities in primary myelofibrosis (PMF) and examines their phenotypic correlates and prognostic significance.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Vol 29, Issue 10, p1356
- ISSN
1527-7755
- Publication type
Journal Article
- DOI
10.1200/JCO.2010.32.9490