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- Title
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.
- Authors
Burris, H A, 3rd; Moore, M J; Andersen, J; Green, M R; Rothenberg, M L; Modiano, M R; Cripps, M C; Portenoy, R K; Storniolo, A M; Tarassoff, P; Nelson, R; Dorr, F A; Stephens, C D; Von Hoff, D D
- Abstract
Most patients with advanced pancreas cancer experience pain and must limit their daily activities because of tumor-related symptoms. To date, no treatment has had a significant impact on the disease. In early studies with gemcitabine, patients with pancreas cancer experienced an improvement in disease-related symptoms. Based on those findings, a definitive trial was performed to assess the effectiveness of gemcitabine in patients with newly diagnosed advanced pancreas cancer.
- Publication
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Vol 15, Issue 6, p2403
- ISSN
0732-183X
- Publication type
Journal Article
- DOI
10.1200/JCO.1997.15.6.2403