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- Title
Alexithymia in PTSD: psychometric and FMRI studies.
- Authors
Frewen, Paul A; Pain, Claire; Dozois, David J A; Lanius, Ruth A
- Abstract
Two studies examined correlates of alexithymia in posttraumatic stress disorder (PTSD). In study 1 (n = 77 individuals with PTSD and 45 controls) Toronto alexithymia scale (TAS-20) scores were positively correlated with PTSD symptoms, dissociation, and childhood abuse and neglect. In study 2, TAS-20 scores were examined as correlates of functional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) response to trauma script imagery. In 16 controls, TAS-20 scores correlated positively with response in medial prefrontal cortex (mPFC), and negatively with response in anterior cingulate cortex (ACC) and thalamus. In 26 individuals with PTSD, TAS-20 scores correlated positively with response in insula, posterior cingulate cortex (PCC), and thalamus, and negatively with response in ACC.
- Publication
Annals of the New York Academy of Sciences, 2006, Vol 1071, p397
- ISSN
0077-8923
- Publication type
Journal Article
- DOI
10.1196/annals.1364.029