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- Title
TREAD: TReatment with Exercise Augmentation for Depression: study rationale and design.
- Authors
Trivedi, Madhukar H; Greer, Tracy L; Grannemann, Bruce D; Church, Timothy S; Galper, Daniel I; Sunderajan, Prabha; Wisniewski, Stephen R; Chambliss, Heather O; Jordan, Alexander N; Finley, Carrie; Carmody, Thomas I
- Abstract
Despite recent advancements in the pharmacological treatment of major depressive disorder (MDD), over half of patients who receive treatment with antidepressant medication do not achieve full remission of symptoms. There is evidence that exercise can reduce depressive symptomatology when used as a treatment for MDD. However, no randomized controlled trials have evaluated exercise as an augmentation strategy for patients with carefully diagnosed MDD who remain symptomatic following an adequate acute phase trial of antidepressant therapy.
- Publication
Clinical trials (London, England), 2006, Vol 3, Issue 3, p291
- ISSN
1740-7745
- Publication type
Journal Article
- DOI
10.1191/1740774506cn151oa